Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy
نویسندگان
چکیده
منابع مشابه
Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy
Sample preparation is critical to biological electron microscopy (EM), and there have been continuous efforts on optimizing the procedures to best preserve structures of interest in the sample. However, a quantitative characterization of the morphological changes associated with each step in EM sample preparation is currently lacking. Using correlative EM and superresolution microscopy (SRM), w...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0176839